SCHEMBL5584055

SCHEMBL5584055

COc1ccnc(C(=O)Nc2ccc(Oc3ccc(-c4ccccc4)cc3)cc2)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCC1 P33527 1/20 0.53
RAB9A P51151 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
PDGFRA P16234 3/20 0.49
AXL P30530 1/20 0.49
KDR P35968 1/20 0.49
FGFR2 P21802 1/20 0.48
PNLIP P16233 1/20 0.47
KIT P10721 2/20 0.47
DHODH Q02127 1/20 0.47
MET P08581 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.46
PKM P14618 1/20 0.46
IDO1 P14902 1/20 0.46
TDO2 P48775 1/20 0.46
PGR P06401 1/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2237038 0.94 RAB9A (0.53) RAB9AMEN1KMT2APDGFRAAXL
SCHEMBL5583655 0.89 RAB9A (0.53) RAB9AMEN1KMT2APDGFRAAXL
SCHEMBL14284589 0.88 RAB9A (0.62) RAB9AMEN1KMT2APDGFRAAXL
SCHEMBL5583670 0.87 KDR (0.55) RAB9AMEN1KMT2APDGFRAAXL
SCHEMBL5583719 0.87 NPC1 (0.53) ABCC1RAB9AMEN1KMT2APDGFRA
SCHEMBL14284595 0.86 KDR (0.55) RAB9AMEN1KMT2APDGFRAAXL
SCHEMBL5583593 0.86 AXL (0.46) RAB9AMEN1KMT2APDGFRAAXL
SCHEMBL14284588 0.85 PGR (0.59) RAB9APDGFRAAXLKDRPGR
SCHEMBL14284575 0.85 GAA (0.58) RAB9AMEN1KMT2APDGFRAAXL
SCHEMBL5583857 0.85 RAB9A (0.51) RAB9AMEN1KMT2APDGFRAAXL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed