SCHEMBL5583787

SCHEMBL5583787

Cc1ccc(Oc2[c]ccc(Oc3ccc(C)cc3)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TEAD4 Q15561 1/20 0.45
ALDH1A1 P00352 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
AR P10275 3/20 0.40
HTT P42858 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37
MMP13 P45452 2/20 0.37
ACHE P22303 1/20 0.37
LPAR1 Q92633 1/20 0.36
LPAR3 Q9UBY5 1/20 0.36
HSD17B1 P14061 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2264146 0.82 TEAD4 (0.47) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL1451634 0.80 LTA4H (0.50) ALDH1A1POLBMAPTHTTMEN1
SCHEMBL21630305 0.79 TEAD4 (0.44) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL920492 0.79 TEAD4 (0.44) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL8124425 0.77 LTA4H (0.47) ALDH1A1TDP1MAPTHTTL3MBTL1
SCHEMBL5583736 0.75 AR (0.51) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL921069 0.74 TEAD4 (0.56) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL1532097 0.74 TEAD4 (0.42) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL83863 0.73 TEAD4 (0.74) TEAD4ALDH1A1TDP1POLBMAPT
SCHEMBL83814 0.73 TEAD4 (0.74) TEAD4ALDH1A1TDP1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US claimed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP claimed
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed