SCHEMBL5583835

SCHEMBL5583835

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.68
MEN1 O00255 1/20 0.68
LMNA P02545 1/20 0.68
MPO P05164 1/20 0.68
MAPT P10636 1/20 0.68
TSHR P16473 1/20 0.68
BLM P54132 1/20 0.68
PMP22 Q01453 1/20 0.68
KMT2A Q03164 1/20 0.68
HIF1A Q16665 1/20 0.68
ACE P12821 3/20 0.63
ECE1 P42892 7/20 0.58
ALOX15 P16050 1/20 0.58
ERAP2 Q6P179 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21641803 1.00 KDM4E (0.68) KDM4EMEN1LMNAMPOMAPT
SCHEMBL29384133 0.98 KDM4E (0.65) KDM4EMEN1LMNAMPOMAPT
SCHEMBL29377160 0.94 ACE (0.62) KDM4EMEN1LMNAMPOMAPT
SCHEMBL31674592 0.94 KDM4E (0.60) KDM4EMEN1LMNAMPOMAPT
SCHEMBL9596908 0.93 ACE (0.72) KDM4EMEN1LMNAMPOMAPT
SCHEMBL11855463 0.93 ACE (0.72) KDM4EMEN1LMNAMPOMAPT
SCHEMBL5583839 0.93 ACE (0.72) KDM4EMEN1LMNAMPOMAPT
SCHEMBL5612810 0.93 ACE (0.72) KDM4EMEN1LMNAMPOMAPT
SCHEMBL9596897 0.93 ACE (0.72) KDM4EMEN1LMNAMPOMAPT
SCHEMBL3359705 0.93 ACE (0.72) KDM4EMEN1LMNAMPOMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12097237-B2 Small molecule Ras inhibitors OHIO STATE INNOVATION FOUNDATION (US) 2024-09-24 US claimed
US-20070207957-A1 Composition For Accelerating Alcohol Metabolism Or Relieving Fatigue By Gluconeogenesis KIRIN BEER KABUSHIKI KAISHA (JP) 2007-09-06 US claimed
EP-1757289-A1 COMPOSITION FOR ACCELERATION OF ALCOHOL METABOLISM OR RECUPERATION FROM FATIGUE THROUGH GLUCONEOGENESIS KIRIN BEER KABUSHIKI KAISHA (JP) 2007-02-28 EP claimed
EP-0457314-A1 Nutrient compositions containing peptides CLINTEC NUTRITION COMPANY (US) 1991-11-21 EP claimed
WO-2026107097-A1 SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF ENLAZA THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
EP-3604503-B1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO KK (JP) 2026-03-18 EP disclosed
US-12492422-B2 Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment Sunbird Bio, Inc. (US) 2025-12-09 US disclosed
US-20250297300-A1 DETECTION, STAGING, MONITORING AND TREATING A DISEASE OR A CONDITION Sunbird Bio, Inc. 2025-09-25 US disclosed
US-20250270512-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO CO., INC. (JP) 2025-08-28 US disclosed
US-20250223627-A1 FLUOROGENIC SUBSTRATES FOR AMINOPEPTIDASE DETECTION IN BIOFLUIDS Sunbird Bio, Inc. 2025-07-10 US disclosed
US-20250215476-A1 EX VIVO PROTEASE ACTIVITY DETECTION FOR HEPATOCELLULAR CARCINOMA Sunbird Bio, Inc. 2025-07-03 US disclosed
WO-2025137586-A2 COMPOSITIONS, METHODS, AND SYSTEMS FOR PROMOTING PHOSPHATE SOLUBILIZATION IN PLANTS Tenfold Technologies, LLC (US) 2025-06-26 WO disclosed
CN-114306389-A Application of periplaneta americana extract in preparation of product for treating stroke recovery 西南大学 2022-04-12 CN disclosed
US-20220062371-A1 LIGAND-DRUG-CONJUGATES AS SUBSTRATES FOR SELECTIVE CLEAVAGE BY THE EXOPEPTIDASE ACTIVITY OF CATHEPSIN B DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) 2022-03-03 US disclosed
US-20200040308-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO CO., INC. (JP) 2020-02-06 US disclosed
EP-3604503-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM Ajinomoto Co., Inc. (JP) 2020-02-05 EP disclosed
CN-102477068-B Amino acid derivative for preparing thrombus dissolving medicament, and preparation method and application thereof UNIV CAPITAL MEDICAL SCIENCES 2013-07-24 CN disclosed
CN-102477068-A Amino acid derivative for preparing thrombus dissolving medicament, and preparation method and application thereof UNIV CAPITAL MEDICAL 2012-05-30 CN disclosed
US-20070207957-A1 Composition For Accelerating Alcohol Metabolism Or Relieving Fatigue By Gluconeogenesis KIRIN BEER KABUSHIKI KAISHA (JP) 2007-09-06 US disclosed
EP-1757289-A1 COMPOSITION FOR ACCELERATION OF ALCOHOL METABOLISM OR RECUPERATION FROM FATIGUE THROUGH GLUCONEOGENESIS KIRIN BEER KABUSHIKI KAISHA (JP) 2007-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12097237-B2 Small molecule Ras inhibitors KRAS, HRAS, NRAS KDM4E 3829/4885MEN1 1244/4885LMNA 3756/4885
US-20220062371-A1 LIGAND-DRUG-CONJUGATES AS SUBSTRATES FOR SELECTIVE CLEAVAGE BY THE EXOPEPTIDASE ACTIVITY OF CATHEPSIN B CTSB, CTSE, CTSV KDM4E 3703/4885MEN1 2492/4885LMNA 2287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.