Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583972 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL299909 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL5583971 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL3323932 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL6680488 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP1A2TSHRHSD17B10 | |
| SCHEMBL12932150 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL23861299 | 0.76 | ALDH1A1 (0.49) | ALDH1A1TDP1CYP1A2TSHRHSD17B10 | |
| SCHEMBL16674748 | 0.76 | ALDH1A1 (0.49) | ALDH1A1TDP1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL11254195 | 0.76 | CYP1A2 (0.50) | ALDH1A1TDP1CYP1A2TSHRSMN1; SMN2 | |
| SCHEMBL29695357 | 0.76 | ALDH1A1 (0.53) | ALDH1A1TDP1CYP1A2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425417-B1 | INTERACTION DETECTION ON SEVERAL PROBE ARRAYS | CLONDIAG CHIP TECH GMBH (DE) | 2007-10-31 | — | — | EP | disclosed |