Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994480 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL299908 | 0.85 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL12932112 | 0.84 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL4303842 | 0.83 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL21240 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL291947 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL12932150 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL21239 | 0.83 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL4067427 | 0.81 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL291949 | 0.81 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2TDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247927-A1 | NOVEL SYSTEMS, METHODS AND COMPOSITIONS FOR THE DIRECT SYNTHESIS OF STICKY ENDED POLYNUCLEOTIDES | THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) | 2020-12-10 | — | — | WO | claimed |
| EP-2427573-A2 | METHOD OF OLIGONUCLEOTIDE LABELING USING CYCLOADDITION REACTION | Chemgenes Corporation (US) | 2012-03-14 | — | — | EP | claimed |
| US-20110009607-A1 | METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END | THE UNIVERSITY OF TOKYO (JP) | 2011-01-13 | — | — | US | claimed |
| EP-2270142-A1 | METHOD OF PREPARING DNA FRAGMENT HAVING STICKY END | The University of Tokyo (JP) | 2011-01-05 | — | — | EP | claimed |
| WO-2010129656-A2 | METHOD OF OLIGONUCLEOTIDE LABELING USING CYCLOADDITION REACTION | CHEMGENES CORPORATION (US) | 2010-11-11 | — | — | WO | claimed |
| US-20220251639-A1 | OLIGONUCLEOTIDE, OMICS ANALYSIS METHOD, AND OMICS ANALYSIS KIT | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2022-08-11 | — | — | US | disclosed |
| US-20220162687-A1 | NOVEL SYSTEMS, METHODS AND COMPOSITIONS FOR THE DIRECT SYNTHESIS OF STICKY ENDED POLYNUCLEOTIDES | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2022-05-26 | — | — | US | disclosed |
| EP-3974528-A1 | OLIGONUCLEOTIDE, OMICS ANALYSIS METHOD, AND OMICS ANALYSIS KIT | Kyushu University, National University Corporation (JP) | 2022-03-30 | — | — | EP | disclosed |
| WO-2020247927-A1 | NOVEL SYSTEMS, METHODS AND COMPOSITIONS FOR THE DIRECT SYNTHESIS OF STICKY ENDED POLYNUCLEOTIDES | THE REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE (US) | 2020-12-10 | — | — | WO | disclosed |
| WO-2020041380-A1 | METHODS AND COMPOSITIONS FOR OPTOCHEMICAL CONTROL OF CRISPR-CAS9 | THE BROAD INSTITUTE, INC. (US) | 2020-02-27 | — | — | WO | disclosed |
| US-8076501-B2 | Photogenerated reagents | LC SCIENCES LC | 2011-12-13 | — | — | US | disclosed |
| US-20110009607-A1 | METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END | THE UNIVERSITY OF TOKYO (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2270142-A1 | METHOD OF PREPARING DNA FRAGMENT HAVING STICKY END | The University of Tokyo (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-20100137600-A1 | Photogenerated reagents | LC SCIENCES LC | 2010-06-03 | — | — | US | disclosed |
| US-7235670-B2 | Photogenerated reagents | Gao, Xiaolian | 2007-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137600-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | ALDH1A1 1813/4885SMN1; SMN2 4876/4885TDP1 2661/4885 |
| US-20110009607-A1 | METHOD FOR PREPARING DNA FRAGMENT HAVING STICKY END | POLB, POLL, POLN | ALDH1A1 2795/4885SMN1; SMN2 4115/4885TDP1 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.