Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680488 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP1A2HSD17B10TDP1 | |
| SCHEMBL29695357 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP1A2HSD17B10TDP1 | |
| SCHEMBL7777994 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP1A2HSD17B10TDP1 | |
| SCHEMBL11254195 | 0.84 | CYP1A2 (0.50) | ALDH1A1TSHRCYP1A2HSD17B10TDP1 | |
| SCHEMBL992973 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP1A2HSD17B10TDP1 | |
| SCHEMBL23861299 | 0.84 | ALDH1A1 (0.49) | ALDH1A1TSHRCYP1A2HSD17B10TDP1 | |
| SCHEMBL16674748 | 0.84 | ALDH1A1 (0.49) | ALDH1A1TSHRCYP1A2HSD17B10TDP1 | |
| SCHEMBL20921370 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP1A2HSD17B10TDP1 | |
| SCHEMBL8125004 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP1A2HSD17B10TDP1 | |
| SCHEMBL11260390 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP1A2HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123486-A1 | Photogenerated reagents | GAO XIAOLIAN (US) | 2013-05-16 | — | — | US | disclosed |
| US-8076501-B2 | Photogenerated reagents | LC SCIENCES LC | 2011-12-13 | — | — | US | disclosed |
| US-20100137600-A1 | Photogenerated reagents | LC SCIENCES LC | 2010-06-03 | — | — | US | disclosed |
| US-7544829-B2 | Photogenerated reagents | LC SCIENCES LC | 2009-06-09 | — | — | US | disclosed |
| US-20080009630-A1 | Photogenerated reagents | LC SCIENCES LC | 2008-01-10 | — | — | US | disclosed |
| US-7235670-B2 | Photogenerated reagents | Gao, Xiaolian | 2007-06-26 | — | — | US | disclosed |
| US-20060122408-A1 | Photogenerated reagents | LC SCIENCES LC | 2006-06-08 | — | — | US | disclosed |
| US-6965040-B1 | Photogenerated reagents | Gao, Xiaolian (US) | 2005-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123486-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | ALDH1A1 1813/4885TSHR 446/4885CYP1A2 221/4885 |
| US-20080009630-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | ALDH1A1 1813/4885TSHR 446/4885CYP1A2 221/4885 |
| US-20060122408-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | ALDH1A1 1813/4885TSHR 446/4885CYP1A2 221/4885 |
| US-20100137600-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | ALDH1A1 1813/4885TSHR 446/4885CYP1A2 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.