Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397041 | 0.88 | ALDH1A1 (0.60) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL5584032 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL28098859 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL3202573 | 0.78 | ALDH1A1 (0.72) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL10628398 | 0.78 | ALDH1A1 (0.49) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL7259696 | 0.78 | ALDH1A1 (0.61) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL10630401 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL7135820 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL5186243 | 0.77 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL5584031 | 0.77 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425417-B1 | INTERACTION DETECTION ON SEVERAL PROBE ARRAYS | CLONDIAG CHIP TECH GMBH (DE) | 2007-10-31 | — | — | EP | disclosed |
| EP-1425417-A2 | INTERACTION DETECTION ON SEVERAL PROBE ARRAYS | Clondiag Chip Technologies GmbH (DE) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003018838-A2 | INTERACTION DETECTION ON SEVERAL PROBE ARRAYS | CLONDIAG CHIP TECHNOLOGIES GMBH (DE) | 2003-03-06 | — | — | WO | disclosed |