Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3766948 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL7254918 | 0.83 | POLB (0.47) | POLBCYP2C19MEN1KMT2A | |
| SCHEMBL10630401 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL3397041 | 0.80 | ALDH1A1 (0.60) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL7260650 | 0.79 | L3MBTL1 (0.46) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL3202573 | 0.78 | ALDH1A1 (0.72) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL6680911 | 0.77 | POLB (0.60) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL11022826 | 0.77 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDCYP2C19MEN1 | |
| SCHEMBL5584033 | 0.77 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL5584031 | 0.77 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDCYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771069-A1 | N-(2-(HYDROXYMETHYL) PHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MICROBICIDAL ACTIVE INGREDIENTS FOR PHYTO-PROTECTION AND THE PROTECTION OF MATERIALS | Bayer CropScience Aktiengesellschaft (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2005074686-A1 | N-(2-(HYDROXYMETHYL) PHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MICROBICIDAL ACTIVE INGREDIENTS FOR PHYTO-PROTECTION AND THE PROTECTION OF MATERIALS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |