Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.34 |
| ▸ | HTR3A | P46098 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | QDPR | P09417 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19756730 | 0.88 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3CYP17A1CHRNA7 | |
| SCHEMBL5584353 | 0.87 | KDM1A (0.41) | SLC6A4SLC6A2SLC6A3CYP17A1CHRNA7 | |
| SCHEMBL8819846 | 0.81 | SLC6A2 (0.37) | SLC6A4SLC6A2SLC6A3CYP17A1CHRNA7 | |
| SCHEMBL19756637 | 0.80 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3CYP17A1CHRNA7 | |
| SCHEMBL20010880 | 0.79 | ESR2 (0.46) | SLC6A4SLC6A2SLC6A3CYP17A1CHRNA7 | |
| SCHEMBL22721036 | 0.76 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3CYP17A1CHRNA7 | |
| Hydrochloric Acid SCHEMBL22721105 | 0.75 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3CYP17A1CHRNA7 | |
| SCHEMBL20010881 | 0.74 | IKBKE (0.38) | SLC6A4SLC6A2SLC6A3CYP17A1CHRNA7 | |
| SCHEMBL19756732 | 0.73 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3CYP17A1CHRNA7 | |
| SCHEMBL4671471 | 0.72 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3BACE1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196199-B2 | Antiserotonine agents; antidepressants | MITSUBISHI PHARMA CORPORATION (JP) | 2007-03-27 | — | — | US | disclosed |
| EP-1188747-B1 | PHENOXYPROPYLAMINE COMPOUNDS | MITSUBISHI PHARMA CORP (JP) | 2005-09-07 | — | — | EP | disclosed |
| US-20040138227-A1 | Phenoxypropylamine compounds | NISHIYAMA AKIRA | 2004-07-15 | — | — | US | disclosed |
| US-6720320-B2 | ANTISEROTONINE AGENTS | MITSUBISHI PHARMA CORPORATION (JP) | 2004-04-13 | — | — | US | disclosed |
| US-20020111358-A1 | Phenoxypropylamine compounds | MITSUBISHI PHARMA CORPORATION (JP) | 2002-08-15 | — | — | US | disclosed |
| EP-1188747-A1 | PHENOXYPROPYLAMINE COMPOUNDS | Mitsubishi Pharma Corporation (JP) | 2002-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138227-A1 | Phenoxypropylamine compounds | HTR1A, HTR1D, HTR5A | SLC6A4 10/4885SLC6A2 21/4885SLC6A3 23/4885 |
| US-20020111358-A1 | Phenoxypropylamine compounds | HTR1A, HTR1D, HTR5A | SLC6A4 10/4885SLC6A2 21/4885SLC6A3 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.