Methionine

Methionine

SCHEMBL162030

CSCC[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 10/20 0.57
BHMT2 Q9H2M3 1/20 0.57
RNPEP Q9H4A4 1/20 0.56
NOS2 P35228 3/20 0.52
NOS3 P29474 2/20 0.52
NOS1 P29475 2/20 0.52
GRM8 O00222 1/20 0.50
GRM6 O15303 1/20 0.50
GRIN2D O15399 1/20 0.50
GRIN3B O60391 1/20 0.50
GSR P00390 1/20 0.50
CYP1A2 P05177 1/20 0.50
GRIK1 P39086 1/20 0.50
GRM5 P41594 1/20 0.50
GRIA1 P42261 1/20 0.50
GRIA2 P42262 1/20 0.50
GRIA3 P42263 1/20 0.50
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Racemethionine SCHEMBL16062299 1.00 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL5584463 1.00 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL9504290 1.00
Racemethionine SCHEMBL5617580 1.00 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL8983115 1.00 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL23361954 1.00 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL287590 1.00 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL4226 1.00
Racemethionine SCHEMBL126688 1.00
Racemethionine SCHEMBL31367634 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024102722-A1 METHODS OF TREATING A TUMOR WITH AN UNMETHYLATED MGMT PROMOTER NEOIMMUNETECH, INC. (US) 2024-05-16 WO claimed
US-20240115675-A1 METHOD OF TREATING A TUMOR WITH A COMBINATION OF AN IL-7 PROTEIN AND A NUCLEOTIDE VACCINE NEOIMMUNETECH, INC. (US) 2024-04-11 US claimed
US-20240101629-A1 USE OF INTERLEUKIN-7 FOR THE TREATMENT OF CORONAVIRUS NEOIMMUNETECH, INC. (US) 2024-03-28 US claimed
US-20240018205-A1 PHARMACEUTICAL COMPOSITION COMPRISING IMMUNOGLOBULIN FC-FUSED INTERLEUKIN-7 FUSION PROTEIN FOR PREVENTING OR TREATING HUMAN PAPILLOMAVIRUS-CAUSED DISEASES GENEXINE, INC. (KR) 2024-01-18 US claimed
US-20230398184-A1 METHODS OF INDUCING STEM CELL MOBILIZATION NEOIMMUNETECH, INC. (US) 2023-12-14 US claimed
EP-4240408-A1 METHOD OF TREATING A TUMOR WITH A COMBINATION OF AN IL-7 PROTEIN AND A NUCLEOTIDE VACCINE NEOIMMUNETECH, INC. (US) 2023-09-13 EP claimed
EP-4236989-A1 USE OF INTERLEUKIN-7 FOR THE TREATMENT OF CORONAVIRUS NeoImmuneTech, Inc. (US) 2023-09-06 EP claimed
EP-4232070-A1 METHODS OF INDUCING STEM CELL MOBILIZATION NeoImmuneTech, Inc. (US) 2023-08-30 EP claimed
CN-116615236-A Methods of treating tumors using combinations of IL-7 proteins and nucleotide vaccines 新免疫技术有限公司 2023-08-18 CN claimed
US-11708399-B2 Pharmaceutical composition comprising immunoglobulin Fc-fused interleukin-7 fusion protein for preventing or treating human papillomavirus-caused diseases GENEXINE, INC. (KR) 2023-07-25 US claimed
CN-108093638-A MODIFIED INTERLEUKIN-7 PROTEIN AND USES THEREOF 格纳西尼有限公司 2018-05-29 CN claimed
EP-3307766-A1 MODIFIED INTERLEUKIN-7 PROTEIN AND USES THEREOF Genexine, Inc. (KR) 2018-04-18 EP claimed
US-20170158746-A1 MODIFIED INTERLEUKIN-7 PROTEIN AND USES THEREOF GENEXINE, INC. (KR) 2017-06-08 US claimed
WO-2017095191-A1 PHARMACEUTICAL COMPOSITION COMPRISING IMMUNOGLOBULIN FC-FUSED INTERLEUKIN-7 FUSION PROTEIN FOR PREVENTING OR TREATING HUMAN PAPILLOMAVIRUS-CAUSED DISEASES 주식회사 제넥신 2017-06-08 WO claimed
WO-2016200219-A1 MODIFIED INTERLEUKIN-7 PROTEIN AND USES THEREOF GENEXINE, INC. (KR) 2016-12-15 WO claimed
US-20100150871-A1 Genetically-modified strain of yeast with an increased production and output of s-adenosylmethionine (sam) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQE (FR) 2010-06-17 US claimed
EP-1805301-A1 GENETICALLY-MODIFIED STRAIN OF YEAST WITH AN INCREASED PRODUCTION AND OUTPUT OF S-ADENOSYLMETHIONINE (SAM) The Centre National de la Recherche Scientifique (FR) 2007-07-11 EP claimed
CN-1325063-C L-amino acid water-soluble pearl powder and its preparing method SONG TINGSHENG (CN) 2007-07-11 CN claimed
WO-2006045953-A1 GENETICALLY-MODIFIED STRAIN OF YEAST WITH AN INCREASED PRODUCTION AND OUTPUT OF S-ADENOSYLMETHIONINE (SAM) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2006-05-04 WO claimed
CN-1709282-A L-amino acid water-soluble pearl powder and its preparing method SONG TINGSHENG (CN) 2005-12-21 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100150871-A1 Genetically-modified strain of yeast with an increased production and output of s-adenosylmethionine (sam) AHCY, MAT2A, MAT1A BHMT 16/4885BHMT2 14/4885RNPEP 555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.