SCHEMBL5584479

SCHEMBL5584479

C=CCc1cc(C2(c3ccc(O)c(C)c3)c3ccccc3-c3ccccc32)ccc1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.70
ESR2 Q92731 3/20 0.70
MAPT P10636 6/20 0.48
MEN1 O00255 6/20 0.48
KMT2A Q03164 6/20 0.48
LMNA P02545 4/20 0.48
POLB P06746 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
NPSR1 Q6W5P4 2/20 0.45
XBP1 P17861 1/20 0.45
AKR1B1 P15121 2/20 0.44
GABRA1 P14867 6/20 0.43
GABRB2 P47870 6/20 0.43
GAA P10253 3/20 0.39
CNR1 P21554 2/20 0.39
CNR2 P34972 2/20 0.39
ALOX5 P09917 1/20 0.39
GABRB1 P18505 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL219581 0.92 ESR1 (0.55) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL30853252 0.92 ESR1 (0.55) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL30306994 0.92 ESR1 (0.55) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL18541606 0.89 ESR1 (0.52) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL15814887 0.87 ESR1 (0.50) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL15814218 0.87 ESR1 (0.50) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL13592688 0.84 ESR1 (0.78) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL19316051 0.84 GABRA1 (0.47) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL70957 0.84 ESR1 (1.00) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL29358768 0.84 ESR1 (1.00) ESR1ESR2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3103831-A1 PHOTO-CURABLE RESIN COMPOSITION AND PHOTO-CURABLE DRY FILM USING THE SAME Shin-Etsu Chemical Co., Ltd. (JP) 2016-12-14 EP disclosed
EP-2447304-A1 Adhesive composition, adhesive sheet, semiconductor apparatus protection material, and semiconductor apperatus Shin-Etsu Chemical Co., Ltd. (JP) 2012-05-02 EP disclosed