SCHEMBL5584853

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5584743	0.80	F2RL3 (0.43)	ARHDAC6F2RL3CYP2C19CYP1A2
	SCHEMBL5584744	0.79	AKR1C3 (0.42)	ARHDAC6F2RL3CYP2C19KDM4E
	SCHEMBL428470	0.78	F2RL3 (0.41)	ARF2RL3CYP2C19KDM4EHSD17B10
	SCHEMBL5584275	0.75	ALDH1A1 (0.38)	HDAC6F2RL3CYP3A4ALDH1A1TP53
	SCHEMBL5584722	0.75	F2RL3 (0.46)	ARF2RL3CYP2C19KDM4ECYP1A2
	SCHEMBL5585409	0.75	F2RL3 (0.39)	ARF2RL3CYP2C19KDM4EHSD17B10
	SCHEMBL5584741	0.75	F2RL3 (0.46)	F2RL3CYP2C19KDM4EHSD17B10CYP3A4
	SCHEMBL5584731	0.73	F2RL3 (0.40)	ARF2RL3CYP2C19KDM4EHSD17B10
	SCHEMBL30176932	0.72	AR (0.68)	ARCYP2C19KDM4EHSD17B10CYP1A2
	SCHEMBL28386646	0.72	AR (0.68)	ARCYP2C19KDM4EHSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.