Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 18/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5584865 | 0.85 | SLC6A9 (0.60) | SLC6A9 | |
| SCHEMBL5590807 | 0.83 | SLC6A9 (0.65) | SLC6A9 | |
| SCHEMBL5584496 | 0.82 | SLC6A9 (0.78) | SLC6A9 | |
| SCHEMBL14538122 | 0.82 | SLC6A9 (0.78) | SLC6A9 | |
| SCHEMBL4282569 | 0.81 | SLC6A9 (0.71) | SLC6A9USP2 | |
| SCHEMBL5584840 | 0.81 | SLC6A9 (0.68) | SLC6A9KDM4EUSP2 | |
| SCHEMBL5585099 | 0.80 | SLC6A9 (0.71) | SLC6A9 | |
| SCHEMBL5585003 | 0.79 | SLC6A9 (0.66) | SLC6A9USP2 | |
| SCHEMBL5584555 | 0.79 | SLC6A9 (0.66) | SLC6A9USP2 | |
| SCHEMBL5584923 | 0.79 | SLC6A9 (0.66) | SLC6A9KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105902-A1 | 4-Phenyl piperdine sulfonyl glycine transporter inhibitors | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
| US-20070105902-A1 | 4-Phenyl piperdine sulfonyl glycine transporter inhibitors | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
| US-20070105902-A1 | 4-Phenyl piperdine sulfonyl glycine transporter inhibitors | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105902-A1 | 4-Phenyl piperdine sulfonyl glycine transporter inhibitors | SLC1A2, SLC1A1, SLC1A3 | SLC6A9 10/4885KDM4E 3080/4885ALDH1A1 1913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.