Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.59 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5585485 | 1.00 | ABCG2 (0.59) | ABCG2TNFRSF1ANPC1RAB9AMAPT | |
| SCHEMBL5585484 | 0.89 | ALDH1A1 (0.59) | ABCG2TNFRSF1ANPC1RAB9AMAPT | |
| SCHEMBL5585477 | 0.89 | ALDH1A1 (0.59) | ABCG2TNFRSF1ANPC1RAB9AMAPT | |
| SCHEMBL5585584 | 0.86 | TNFRSF1A (0.75) | ABCG2TNFRSF1ANPC1RAB9AMAPT | |
| SCHEMBL5585582 | 0.86 | TNFRSF1A (0.75) | ABCG2TNFRSF1ANPC1RAB9AMAPT | |
| SCHEMBL5585779 | 0.85 | ALDH1A1 (0.63) | ABCG2TNFRSF1ANPC1RAB9AMAPT | |
| SCHEMBL5585775 | 0.85 | ALDH1A1 (0.63) | ABCG2TNFRSF1ANPC1RAB9AMAPT | |
| SCHEMBL5585538 | 0.85 | ABCG2 (0.56) | ABCG2TNFRSF1ANPC1MAPTLMNA | |
| SCHEMBL5585541 | 0.85 | ABCG2 (0.56) | ABCG2TNFRSF1ANPC1MAPTLMNA | |
| SCHEMBL9365255 | 0.83 | CYP1A2 (0.67) | NPC1RAB9AMAPTLMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-20050176994-A1 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | SANKIO CHEMICAL CO., LTD. (JP) | 2005-08-11 | — | — | US | disclosed |
| EP-1505054-A1 | PROCESS FOR PRODUCING 4-PHENYL-4-OXO-2-BUTENOIC ESTER DERIVATIVE | Sankio Chemical Co., Ltd. (JP) | 2005-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176994-A1 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | HPD, PAH, CYP4A11 | ABCG2 2485/4885TNFRSF1A 4317/4885NPC1 4367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.