Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5585775 | 1.00 | ALDH1A1 (0.63) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5585922 | 0.88 | MEN1 (0.66) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL5585927 | 0.88 | MEN1 (0.66) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL5585485 | 0.85 | ABCG2 (0.59) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5585475 | 0.85 | ABCG2 (0.59) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19074825 | 0.81 | NPC1 (0.74) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5585484 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HTTKMT2AMEN1NPC1 | |
| SCHEMBL5585477 | 0.81 | ALDH1A1 (0.59) | ALDH1A1HTTKMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL9639136 | 0.80 | NPC1 (0.72) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5585538 | 0.77 | ABCG2 (0.56) | ALDH1A1KMT2AMEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-20050176994-A1 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | SANKIO CHEMICAL CO., LTD. (JP) | 2005-08-11 | — | — | US | disclosed |
| EP-1505054-A1 | PROCESS FOR PRODUCING 4-PHENYL-4-OXO-2-BUTENOIC ESTER DERIVATIVE | Sankio Chemical Co., Ltd. (JP) | 2005-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176994-A1 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | HPD, PAH, CYP4A11 | ALDH1A1 1038/4885HTT 2460/4885KMT2A 1717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.