Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2839428 | 0.91 | TSHR (0.44) | TSHRALDH1A1THRBTDP1 | |
| SCHEMBL1899385 | 0.87 | ALDH1A1 (0.46) | TSHRALDH1A1THRBTDP1 | |
| SCHEMBL7186339 | 0.84 | TSHR (0.47) | TSHRALDH1A1THRBTDP1 | |
| SCHEMBL7708053 | 0.79 | ALDH1A1 (0.39) | TSHRALDH1A1THRBTDP1 | |
| SCHEMBL1525545 | 0.79 | TSHR (0.50) | TSHRALDH1A1THRBTDP1 | |
| SCHEMBL16537559 | 0.78 | TSHR (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL2846496 | 0.78 | TSHR (0.40) | TSHRALDH1A1THRB | |
| SCHEMBL5838837 | 0.78 | TSHR (0.53) | TSHRALDH1A1THRB | |
| SCHEMBL15798263 | 0.77 | TSHR (0.37) | TSHRALDH1A1THRB | |
| SCHEMBL16537044 | 0.77 | TSHR (0.49) | TSHRALDH1A1THRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241009-B2 | Crosslinking of silicones presence of functionalized silicones | CALHOUN VISION, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| EP-1781212-A2 | CROSSLINKING OF SILICONES | Calhoun Vision, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006002201-A2 | CROSSLINKING OF SILICONES | CALHOUN VISION, INC. (US) | 2006-01-05 | — | — | WO | disclosed |
| US-20050018310-A1 | Crosslinking of silicones presence of functionalized silicones | RXSIGHT, INC. | 2005-01-27 | — | — | US | disclosed |