Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.34 |
| ▸ | CES2 | O00748 | 5/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 4/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837803 | 0.98 | TSHR (0.56) | TSHRALDH1A1THRBEPHX1CES2 | |
| SCHEMBL5838801 | 0.98 | TSHR (0.56) | TSHRALDH1A1THRBEPHX1CES2 | |
| SCHEMBL5838520 | 0.98 | TSHR (0.56) | TSHRALDH1A1THRBEPHX1CES2 | |
| SCHEMBL5838917 | 0.96 | TSHR (0.55) | TSHRALDH1A1THRBEPHX1CES2 | |
| SCHEMBL1525545 | 0.94 | TSHR (0.50) | TSHRALDH1A1THRBEPHX1CES2 | |
| SCHEMBL15826448 | 0.88 | TSHR (0.47) | TSHRALDH1A1THRBEPHX1CES2 | |
| SCHEMBL23346282 | 0.87 | TSHR (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL10408288 | 0.87 | ALDH1A1 (0.54) | TSHRALDH1A1THRBEPHX1FAAH | |
| SCHEMBL7186339 | 0.86 | TSHR (0.47) | TSHRALDH1A1THRBTHRACES1 | |
| SCHEMBL2839428 | 0.85 | TSHR (0.44) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252953-A1 | Process for the production of silyl carboxylate monomers | SIGMA COATINGS B.V. (NL) | 2006-11-09 | — | — | US | claimed |
| EP-1572702-A1 | PROCESS FOR THE PRODUCTION OF SILYL CARBOXYLATE MONOMERS | SIGMA COATINGS B.V. (NL) | 2005-09-14 | — | — | EP | claimed |
| WO-2004056838-A1 | PROCESS FOR THE PRODUCTION OF SILYL CARBOXYLATE MONOMERS | SIGMA COATINGS B.V. (NL) | 2004-07-08 | — | — | WO | claimed |
| EP-1431301-A1 | Process for the production of silyl carboxylate monomers | SIGMA COATINGS B.V. (NL) | 2004-06-23 | — | — | EP | claimed |
| US-20060276113-A1 | Polishing cloth, polishing apparatus and method of manufacturing semiconductor devices | HIRABAYASHI HIDEAKI | 2006-12-07 | — | — | US | disclosed |
| US-20060252953-A1 | Process for the production of silyl carboxylate monomers | SIGMA COATINGS B.V. (NL) | 2006-11-09 | — | — | US | disclosed |
| US-20040236130-A1 | Process for the preparation of trialkylsilated carboxylate monomers, the obatined trialkylsilated carboxylate monomers and their use in anti-fouling coatings | SIGMA COATINGS B.V. (NL) | 2004-11-25 | — | — | US | disclosed |
| EP-1431301-A1 | Process for the production of silyl carboxylate monomers | SIGMA COATINGS B.V. (NL) | 2004-06-23 | — | — | EP | disclosed |
| EP-1389214-A1 | PROCESS FOR THE PREPARATION OF TRIALKYLSILYLATED CARBOXYLATE MONOMERS, THE OBTAINED TRIALKYLSILYLATED CARBOXYLATE MONOMERS AND THEIR USE IN ANTI-FOULING COATINGS | SIGMA COATINGS B.V. (NL) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094838-A1 | PROCESS FOR THE PREPARATION OF TRIALKYLSILYLATED CARBOXYLATE MONOMERS, THE OBTAINED TRIALKYLSILYLATED CARBOXYLATE MONOMERS AND THEIR USE IN ANTI-FOULING COATINGS | SIGMA COATINGS B.V. (NL) | 2002-11-28 | — | — | WO | disclosed |
| EP-1260513-A1 | Process for the preparation of trialkylsilylated carboxylate monomers, the obtained trialkylsilylated carboxylate monomers and their use in antifouling coatings | SIGMA COATINGS B.V. (NL) | 2002-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252953-A1 | Process for the production of silyl carboxylate monomers | ACSL1, SUCLA2, MSMO1 | TSHR 4873/4885ALDH1A1 47/4885THRB 4691/4885 |
| US-20040236130-A1 | Process for the preparation of trialkylsilated carboxylate monomers, the obatined trialkylsilated carboxylate monomers and their use in anti-fouling coatings | ACMSD, OR10J3, CFD | TSHR 3555/4885ALDH1A1 223/4885THRB 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.