SCHEMBL2839428

SCHEMBL2839428

C=C(C)C(=O)O[Si](CCC)(CCC)CCC

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.42
THRB P10828 1/20 0.41
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5585580 0.91 TSHR (0.41) TSHRALDH1A1THRBTDP1
SCHEMBL1525545 0.87 TSHR (0.50) TSHRALDH1A1THRBTDP1
SCHEMBL5838837 0.85 TSHR (0.53) TSHRALDH1A1THRB
SCHEMBL5838801 0.84 TSHR (0.56) TSHRALDH1A1THRBTDP1
SCHEMBL5837803 0.84 TSHR (0.56) TSHRALDH1A1THRBTDP1
SCHEMBL5838520 0.84 TSHR (0.56) TSHRALDH1A1THRBTDP1
SCHEMBL5838917 0.82 TSHR (0.55) TSHRALDH1A1THRBTDP1
SCHEMBL1899385 0.81 ALDH1A1 (0.46) TSHRALDH1A1THRBTDP1
SCHEMBL23346282 0.81 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL10408288 0.81 ALDH1A1 (0.54) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111534186-B Fluorescent visual fluorine-silicon electronic protective coating and preparation method thereof 浙江大学 2021-04-23 CN claimed
CN-111534186-A Fluorescent visual fluorine-silicon electronic protective coating and preparation method thereof 浙江大学 2020-08-14 CN claimed
US-20060252953-A1 Process for the production of silyl carboxylate monomers SIGMA COATINGS B.V. (NL) 2006-11-09 US claimed
EP-1572702-A1 PROCESS FOR THE PRODUCTION OF SILYL CARBOXYLATE MONOMERS SIGMA COATINGS B.V. (NL) 2005-09-14 EP claimed
WO-2004056838-A1 PROCESS FOR THE PRODUCTION OF SILYL CARBOXYLATE MONOMERS SIGMA COATINGS B.V. (NL) 2004-07-08 WO claimed
EP-1431301-A1 Process for the production of silyl carboxylate monomers SIGMA COATINGS B.V. (NL) 2004-06-23 EP claimed
CN-113444418-B Antifouling coating composition 中国涂料株式会社 2024-02-13 CN disclosed
CN-111187548-B Fluorosilicone composite photocatalytic antibacterial antifouling paint and preparation method thereof 浙江大学衢州研究院 2021-11-30 CN disclosed
CN-111187530-B Fluorine-silicon composite visible light catalytic antibacterial antifouling paint and preparation method thereof 浙江大学衢州研究院 2021-11-26 CN disclosed
CN-113444418-A Antifouling coating composition 中国涂料株式会社 2021-09-28 CN disclosed
CN-111534186-B Fluorescent visual fluorine-silicon electronic protective coating and preparation method thereof 浙江大学 2021-04-23 CN disclosed
US-10858521-B2 Antifouling coating compositions, antifouling coating films, antifouling substrates, methods for producing antifouling substrates, and methods of storing antifouling coating compositions CHUGOKU MARINE PAINTS, LTD. (JP) 2020-12-08 US disclosed
CN-111534186-A Fluorescent visual fluorine-silicon electronic protective coating and preparation method thereof 浙江大学 2020-08-14 CN disclosed
EP-0775733-B1 ANTIFOULING PAINT COMPOSITION, COATING FILM MADE FROM THE COMPOSITION, ANTIFOULING METHOD USING THE COMPOSITION, AND HULLS OR SUBMARINE STRUCTURES COVERED WITH THE COATING FILM CHUGOKU MARINE PAINTS (JP) 2002-09-04 EP disclosed
EP-1227111-A1 TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF Yoshitomi Fine Chemicals, Ltd. (JP) 2002-07-31 EP disclosed
EP-1080640-A1 COATED BIS(2-PYRIDINETHIOL 1-OXIDE) COPPER SALT Yoshitomi Fine Chemicals, Ltd. (JP) 2001-03-07 EP disclosed
US-6172132-B1 ANTIFOULING AGENT, FILM FORMING COPOLYMER OF AN (METH)ACRYLIC ACID ESTER AND A TRIALKYLSILYL (METH)ACRYLATE OF GIVEN FORMULA, AND CHLORINATED PARAFFIN OF 8-30 CARBON ATOMS AND GIVEN CHLORINE CONTENT; STORAGE STABILITY, CRACK RESISTANCE CHUGOKO MARINE PAINTS LTD (JP) 2001-01-09 US disclosed
US-6110990-A CRACKING RESISTANCE AND HAVING SELF-POLISHING PROPERTIES SUCH THAT ADHERENCE OF AQUATIC ORGANISM TO SHIP BOTTOMS, UNDERWATER STRUCTURES, FISHING NETS CAN EFFECTIVELY PREVENTED; STORAGE STABILITY CHUGOKU MARINE PAINTS LTD (JP) 2000-08-29 US disclosed
CN-1155896-A Antifouling coating composition, coating film formed therefrom, and method of using same CHUGOKU MARINE PAINTS (JP) 1997-07-30 CN disclosed
EP-0775733-A1 ANTIFOULING PAINT COMPOSITION, COATING FILM MADE FROM THE COMPOSITION, ANTIFOULING METHOD USING THE COMPOSITION, AND HULLS OR SUBMARINE STRUCTURES COVERED WITH THE COATING FILM CHUGOKU MARINE PAINTS, LTD. (JP) 1997-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252953-A1 Process for the production of silyl carboxylate monomers ACSL1, SUCLA2, MSMO1 TSHR 4873/4885ALDH1A1 47/4885THRB 4691/4885
US-10858521-B2 Antifouling coating compositions, antifouling coating films, antifouling substrates, methods for producing antifouling substrates, and methods of storing antifouling coating compositions ITGA5, SIGMAR1, ITGB6 TSHR 720/4885ALDH1A1 930/4885THRB 732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.