SCHEMBL558565

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1823549	0.81	NOS3 (0.45)	NOS3NOS2NOS1PDPK1ABL1
	SCHEMBL558700	0.81	NOS3 (0.45)	NOS3NOS2NOS1PDPK1ABL1
	SCHEMBL6844953	0.79	CYP1A2 (0.43)	NOS3NOS2NOS1CYP1A2CYP2A6
	SCHEMBL21650222	0.73	NOS3 (0.45)	NOS3NOS2NOS1PDPK1ABL1
	SCHEMBL10271766	0.73	NOS3 (0.40)	NOS3NOS2NOS1CYP1A2CYP2A6
	SCHEMBL10220707	0.73	CYP1A2 (0.38)	NOS3NOS2NOS1CYP1A2CYP2A6
	SCHEMBL14391805	0.72	PSMD14 (0.41)	NOS3NOS2NOS1ABL1MAP4K1
	SCHEMBL27037400	0.72	NOS3 (0.43)	NOS3NOS2NOS1PDPK1ABL1
	SCHEMBL557986	0.70	NOS3 (0.62)	NOS3NOS2NOS1PDPK1ABL1
	SCHEMBL3844867	0.70	CYP1A2 (0.46)	NOS3NOS2NOS1CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.