SCHEMBL5586237

SCHEMBL5586237

O=C1OC2(c3ccc(O)c(I)c3Oc3c(I)c(O)c(I)c(I)c32)c2c(Cl)c(Cl)c(Cl)c(Cl)c21.[NaH].[NaH]

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMAD3 P84022 1/20 0.65
THRB P10828 3/20 0.61
RECQL P46063 3/20 0.61
TDP1 Q9NUW8 3/20 0.61
MEN1 O00255 2/20 0.61
BLM P54132 2/20 0.61
KMT2A Q03164 2/20 0.61
GLB1 P16278 1/20 0.61
CTRC Q99895 1/20 0.61
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
CASP1 P29466 1/20 0.47
BRCA1 P38398 1/20 0.47
HIF1A Q16665 1/20 0.47
HSD17B10 Q99714 1/20 0.47
GNG2 P59768 1/20 0.38
GNB1 P62873 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10495599 1.00 SMAD3 (0.65) SMAD3THRBRECQLTDP1MEN1
SCHEMBL6821888 0.99 SMAD3 (0.66) SMAD3THRBRECQLTDP1MEN1
SCHEMBL23389672 0.92 SMAD3 (0.69) SMAD3THRBRECQLTDP1MEN1
SCHEMBL1444969 0.89 SMAD3 (0.77) SMAD3THRBRECQLTDP1MEN1
SCHEMBL23389601 0.86 SMAD3 (0.66) SMAD3THRBRECQLTDP1MEN1
SCHEMBL23860296 0.86 SMAD3 (0.66) SMAD3THRBRECQLTDP1MEN1
SCHEMBL1444919 0.85 THRB (0.85) SMAD3THRBRECQLTDP1MEN1
SCHEMBL23860297 0.82 RECQL (0.57) SMAD3THRBRECQLTDP1MEN1
SCHEMBL4574704 0.79 SMAD3 (0.61) SMAD3THRBRECQLTDP1MEN1
SCHEMBL1464072 0.78 SMAD3 (0.82) SMAD3THRBRECQLTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7166008-B2 Method of curing using an electroluminescent light 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-01-23 US disclosed
WO-2005068523-A1 METHOD OF CURING USING AN ELECTROLUMINESCENT LIGHT 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-07-28 WO disclosed
US-20050136210-A1 Method of curing using an electroluminescent light 3M INNOVATIVE PROPERTIES COMPANY 2005-06-23 US disclosed