SCHEMBL5587008

SCHEMBL5587008

CO[Si](OC)(OCc1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
IDO1 P14902 1/20 0.40
AGXT P21549 1/20 0.39
ALDH1A1 P00352 2/20 0.38
MAOB P27338 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 2/20 0.36
HPGD P15428 1/20 0.36
LTA4H P09960 1/20 0.35
TP53 P04637 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
CYP1A2 P05177 1/20 0.34
PTGS1 P23219 1/20 0.34
SLC6A2 P23975 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17391584 0.96 TSHR (0.43) TSHRIDO1AGXTALDH1A1MAOB
SCHEMBL17391615 0.87 TSHR (0.50) TSHRIDO1AGXTALDH1A1MAOB
SCHEMBL28236304 0.84 IDO1 (0.35) TSHRIDO1AGXTALDH1A1MAOB
SCHEMBL28900359 0.81 ALDH1A1 (0.40) TSHRIDO1AGXTALDH1A1MAOB
SCHEMBL8637212 0.81 TSHR (0.40) TSHRIDO1AGXTALDH1A1MAOB
SCHEMBL28872334 0.80 AGXT (0.43) TSHRIDO1AGXTALDH1A1MAOB
SCHEMBL1225533 0.79 TSHR (0.33) TSHRALDH1A1MAPK1HPGDLTA4H
SCHEMBL17391526 0.78 TSHR (0.41) TSHRIDO1AGXTALDH1A1MAOB
SCHEMBL17714486 0.78 IDO1 (0.47) IDO1L3MBTL1TDP1LMNA
SCHEMBL37986 0.78 CA4 (0.41) TSHRALDH1A1MAPTMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115897284-B Production method of waterproof wear-resistant corrugated board 杭州永晶科技有限公司 2024-02-09 CN claimed
CN-117485011-A Preparation method of microwave composite dielectric substrate with low dielectric constant and low thermal expansion coefficient 中国电子科技集团公司第四十六研究所 2024-02-02 CN claimed
CN-115897284-A Production method of waterproof wear-resistant corrugated board 杭州永晶科技有限公司 2023-04-04 CN claimed
CN-109762013-A Melamine cyanurate with silane structure, preparation method and its application 杭州捷尔思阻燃化工有限公司 2019-05-17 CN claimed
EP-0731114-A1 Process for obtaining ethylene-propylene elastomer copolymers with a high purity and controlled molecular weight distribution ENICHEM ELASTOMERI S.r.l. (IT) 1996-09-11 EP claimed
EP-0492966-B1 A stereospecific catalyst system intended for the polymerization of olefins BOREALIS AS (DK) 1996-08-21 EP claimed
EP-0492966-A2 A stereospecific catalyst system intended for the polymerization of olefins BOREALIS A/S (DK) 1992-07-01 EP claimed
CN-115897284-B Production method of waterproof wear-resistant corrugated board 杭州永晶科技有限公司 2024-02-09 CN disclosed
CN-117485011-A Preparation method of microwave composite dielectric substrate with low dielectric constant and low thermal expansion coefficient 中国电子科技集团公司第四十六研究所 2024-02-02 CN disclosed
CN-114055975-B Ink jet recording method and ink jet recording apparatus 精工爱普生株式会社 2023-05-12 CN disclosed
CN-115897284-A Production method of waterproof wear-resistant corrugated board 杭州永晶科技有限公司 2023-04-04 CN disclosed
CN-110199367-B Electrolytic solution for electrolytic capacitor, and method for manufacturing electrolytic capacitor 日本贵弥功株式会社 2021-11-26 CN disclosed
CN-109081921-B Silicon-based hard mask 罗门哈斯电子材料有限责任公司 2021-07-06 CN disclosed
US-6127041-A FUSER MEMBER HAVING A SUPPORT METALLIC CORE AND A LAYER OF MATERIAL FORMED OVER THE METALLIC CORE EASTMAN KODAK COMPANY (US) 2000-10-03 US disclosed
US-5960245-A METALLIC CORE WITH CROSSLINKED POLYSILOXANE OVERCOATING EASTMAN KODAK COMPANY (US) 1999-09-28 US disclosed
EP-0739917-B1 A continuous process for preparation of highly rigid propylene-ethylene block copolymers CHISSO CORP (JP) 1999-01-27 EP disclosed
US-5854355-A Continuous process for preparation of highly rigid propylene-ethylene block copolymers CHISSO CORPORATION (JP) 1998-12-29 US disclosed
EP-0739917-A1 A continuous process for preparation of highly rigid propylene-ethylene block copolymers CHISSO CORPORATION (JP) 1996-10-30 EP disclosed
EP-0580370-A1 High rubber damping composition SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 1994-01-26 EP disclosed
US-4609427-A HIGH PRECISION AND RELIABILITY CANON KABUSHIKI KAISHA (JP) 1986-09-02 US disclosed