SCHEMBL5587537

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5590041	0.84	VCAM1 (0.40)	LMNAGLRA3GLRBVCAM1GABBR2
	SCHEMBL5588061	0.83	GLRA3 (0.42)	TP53CA1CA2GLRA3GLRB
	SCHEMBL5590050	0.82	PTGS1 (0.40)	LMNATP53GLRA3GLRBVCAM1
	SCHEMBL5587149	0.81	VCAM1 (0.39)	VCAM1
	SCHEMBL5587534	0.80	ALOX15 (0.55)	LMNATP53CYP3A4HPGDALOX15
	SCHEMBL5588379	0.80	GLRA3 (0.42)	CA1CA2GLRA3GLRBVCAM1
	SCHEMBL5589695	0.80	GLRA3 (0.42)	CA1CA2GLRA3GLRBVCAM1
	SCHEMBL11777253	0.78	GLRA3 (0.61)	LMNATP53CYP3A4HPGDALOX15
	SCHEMBL5586771	0.78	VCAM1 (0.37)	VCAM1
	SCHEMBL5588758	0.78	GLRA3 (0.40)	GLRA3GLRBVCAM1GABBR2GABBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.