SCHEMBL5587878

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5589033	0.93	KDM4E (0.45)	KDM4EALDH1A1HSD17B10TDP1MAPT
	SCHEMBL1438740	0.83	HSD17B10 (0.52)	KDM4EALDH1A1HSD17B10TDP1MAPT
	SCHEMBL5587825	0.83	APP (0.47)	KDM4EALDH1A1HSD17B10TDP1MAPT
	SCHEMBL29141732	0.80	HSD17B10 (0.54)	KDM4EALDH1A1HSD17B10TDP1MAPT
	SCHEMBL5588402	0.78	PSMG3 (0.48)	KDM4EALDH1A1HSD17B10TDP1MAPT
	SCHEMBL5588135	0.78	APP (0.41)	KDM4EALDH1A1HSD17B10TDP1MAPT
	SCHEMBL5590326	0.78	KDM4E (0.38)	KDM4EALDH1A1HSD17B10TDP1MAPT
	SCHEMBL619426	0.77	HSD17B10 (0.40)	KDM4EALDH1A1HSD17B10TDP1MAPT
	SCHEMBL29047180	0.77	MAPT (0.50)	KDM4EALDH1A1HSD17B10MAPTCYP3A4
	SCHEMBL678486	0.76	KCNA3 (0.53)	CYP3A4MEN1HPGDKMT2AKCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.