SCHEMBL5589476

SCHEMBL5589476

CC(=Nc1ccccc1)c1cccc(C(C)=Nc2ccccc2)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 5/20 0.50
NOS3 P29474 3/20 0.50
KDM4E B2RXH2 4/20 0.41
ALOX15 P16050 2/20 0.41
HTR3E A5X5Y0 2/20 0.41
HTR3B O95264 2/20 0.41
HTR3A P46098 2/20 0.41
HTR3D Q70Z44 2/20 0.41
HTR3C Q8WXA8 2/20 0.41
TSHR P16473 1/20 0.41
ACMSD Q8TDX5 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
PLAU P00749 1/20 0.41
ALDH1A1 P00352 4/20 0.41
MAPT P10636 4/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5589473 1.00 NOS1 (0.50) NOS1NOS3KDM4EALOX15HTR3E
SCHEMBL15082887 0.98 NOS1 (0.48) NOS1NOS3KDM4EALOX15HTR3E
SCHEMBL5589766 0.98 NOS1 (0.48) NOS1NOS3KDM4EALOX15HTR3E
Hydrochloric Acid SCHEMBL7179350 0.96 NOS1 (0.47) NOS1NOS3KDM4EALOX15HTR3E
Hydrochloric Acid SCHEMBL7182691 0.96 NOS1 (0.47) NOS1NOS3KDM4EALOX15HTR3E
Hydrochloric Acid SCHEMBL7171334 0.96 NOS1 (0.47) NOS1NOS3KDM4EALOX15HTR3E
Hydrochloric Acid SCHEMBL7176633 0.96 NOS1 (0.47) NOS1NOS3KDM4EALOX15HTR3E
Hydrochloric Acid SCHEMBL7175793 0.96 NOS1 (0.47) NOS1NOS3KDM4EALOX15HTR3E
SCHEMBL17489134 0.91 KDM4E (0.59) NOS1NOS3KDM4EALOX15TSHR
SCHEMBL21113696 0.91 KDM4E (0.44) NOS1NOS3KDM4EALOX15HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239957-A1 ALKOXYLATED POLYMERS SUN CHEMICAL CORPORATION (US) 2024-07-18 US claimed
US-11912821-B2 Alkoxylated polymers SUN CHEMICAL CORPORATION (US) 2024-02-27 US claimed
US-11078336-B2 Alkoxylated dispersing agents SUN CHEMICAL CORPORATION (US) 2021-08-03 US claimed
EP-3373926-B1 ALKOXYLATED DISPERSING AGENTS SUN CHEMICAL CORP (US) 2020-06-10 EP claimed
US-20190322813-A1 ALKOXYLATED DISPERSING AGENTS SUN CHEMICAL CORPORATION (US) 2019-10-24 US claimed
EP-3145963-B1 ALKOXYLATED POLYMERS SUN CHEMICAL CORP (US) 2019-07-10 EP claimed
US-20190144604-A1 ALKOXYLATED POLYMERS SUN CHEMICAL CORPORATION (US) 2019-05-16 US claimed
EP-3373926-A1 ALKOXYLATED DISPERSING AGENTS Sun Chemical Corporation (US) 2018-09-19 EP claimed
WO-2017083321-A1 ALKOXYLATED DISPERSING AGENTS SUN CHEMICAL CORPORATION (US) 2017-05-18 WO claimed
US-20170101505-A1 ALKOXYLATED POLYMERS SUN CHEMICAL CORPORATION (US) 2017-04-13 US claimed
WO-2015179626-A1 ALKOXYLATED POLYMERS SUN CHEMICAL CORPORATION (US) 2015-11-26 WO claimed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP claimed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP claimed
US-6864334-B2 Multi-dentate late transition metal catalyst complexes and polymerization methods using those complexes EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2005-03-08 US claimed
US-20050004334-A1 MULTI-DENTATE LATE TRANSITION METAL CATALYST COMPLEXES AND POLYMERIZATION METHODS USING THOSE COMPLEXES BOFFA LISA SAUNDERS (US) 2005-01-06 US claimed
US-20040254067-A1 Multi-dentate late transition metal catalyst complexes and polymerization methods using those complexes BOFFA LISA SAUNDERS (US) 2004-12-16 US claimed
US-6809058-B2 CU, AG AND AU COMPLEXES HAVING A MULTIDENTATE NITROGEN-CONTAINING LIGAND, SUCH AS 2,2':6',2'-TERPYRIDINE, (2,6-BIS(1-PHENYLIMINO) ETHYL)PYRIDINE, 1,4,7-TRIAZACYCLONONANE, OR THEIR SUBSTITUTED DERIVATIVES. EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2004-10-26 US claimed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO claimed
US-20030069128-A1 Multi-dentate late transition metal catalyst complexes and polymerization methods using those complexes EXXONMOBIL RESEARCH & ENGINEERING COMPANY 2003-04-10 US claimed
WO-2003020778-A1 MULTI-DENTATE LATE TRANSITION METAL CATALYST COMPLEXES AND POLYMERIZATION METHODS USING THOSE COMPLEXES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2003-03-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050004334-A1 MULTI-DENTATE LATE TRANSITION METAL CATALYST COMPLEXES AND POLYMERIZATION METHODS USING THOSE COMPLEXES NOX3, CA3, KCNN4 NOS1 297/4885NOS3 114/4885KDM4E 3246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.