SCHEMBL5589774

SCHEMBL5589774

CCc1c(O)c(O)c(Cl)c(CC)c1CC

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.32
HSD17B10 Q99714 3/20 0.32
MEN1 O00255 2/20 0.32
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
TSHR P16473 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 2/20 0.31
MAPK1 P28482 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP2C9 P11712 1/20 0.31
NPC1 O15118 1/20 0.30
USP2 O75604 1/20 0.30
EGFR P00533 1/20 0.30
ESR1 P03372 1/20 0.30
ERBB2 P04626 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5588710 0.90 TSHR (0.38) HPGDHSD17B10MEN1LMNAMAPT
SCHEMBL5587147 0.83 GABRA1 (0.36)
SCHEMBL5588038 0.79 TSHR (0.45) HPGDHSD17B10MEN1LMNAMAPT
SCHEMBL3679962 0.76 GABRA1 (0.36)
SCHEMBL7179070 0.75 HPGD (0.35) HPGDHSD17B10MEN1LMNAMAPT
SCHEMBL11592887 0.74 GABRA1 (0.35)
SCHEMBL5588218 0.73 LDHA (0.37) HPGDHSD17B10
SCHEMBL5590621 0.73 AHR (0.33)
SCHEMBL23716795 0.73 GABRA1 (0.38) HSPA5ALOX15ALOX12
SCHEMBL1760474 0.73 GABRA1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 HPGD 2689/4885HSD17B10 1640/4885MEN1 3377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.