Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5589352 | 0.99 | SIGMAR1 (0.43) | SIGMAR1CYP1A2CYP2A6NOS3NOS1 | |
| SCHEMBL5590427 | 0.84 | SIGMAR1 (0.36) | SIGMAR1CYP1A2CYP2A6 | |
| SCHEMBL5586653 | 0.82 | SIGMAR1 (0.39) | SIGMAR1CYP1A2CYP2A6MAPK1ALDH1A1 | |
| SCHEMBL5587396 | 0.82 | TRPA1 (0.37) | SIGMAR1CYP1A2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL5588761 | 0.82 | SIGMAR1 (0.36) | SIGMAR1CYP1A2CYP2A6TSHR | |
| SCHEMBL5588276 | 0.81 | TRPA1 (0.38) | SIGMAR1CYP1A2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL5588047 | 0.81 | SIGMAR1 (0.39) | SIGMAR1CYP1A2CYP2A6MAPK1ALDH1A1 | |
| SCHEMBL5588043 | 0.81 | SIGMAR1 (0.39) | SIGMAR1CYP1A2CYP2A6MAPK1ALDH1A1 | |
| SCHEMBL8094733 | 0.80 | MAPT (0.35) | NOS3NOS1NOS2MAPK1ALDH1A1 | |
| SCHEMBL8094736 | 0.80 | MAPT (0.35) | NOS3NOS1NOS2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247687-B2 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-07-24 | — | — | US | disclosed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | SIGMAR1 1143/4885CYP1A2 2390/4885CYP2A6 2765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.