SCHEMBL5589985

SCHEMBL5589985

CC1=CC(C(C)C)=C(C)C(=O)C1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EEF2K O00418 1/20 0.37
PLK1 P53350 1/20 0.37
PLK2 Q9NYY3 1/20 0.37
IDO1 P14902 2/20 0.35
MEN1 O00255 1/20 0.35
PLIN1 O60240 1/20 0.35
NR1I2 O75469 1/20 0.35
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GSR P00390 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
GAA P10253 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
HSPD1 P10809 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5586954 0.65 MEN1 (0.33) IDO1MEN1PLIN1NR1I2USP2
SCHEMBL5588355 0.65 MEN1 (0.33) IDO1MEN1PLIN1NR1I2USP2
SCHEMBL5588222 0.65 MEN1 (0.33) IDO1MEN1PLIN1NR1I2USP2
SCHEMBL5590100 0.62 CDC25A (0.32) CDC25ACDC25B
SCHEMBL5038101 0.62 EEF2K (0.46) EEF2KPLK1PLK2IDO1MEN1
SCHEMBL11738492 0.62 EEF2K (0.41) EEF2KPLK1PLK2IDO1MEN1
SCHEMBL5589993 0.62 MAPT (0.36) IDO1MEN1PLIN1NR1I2USP2
SCHEMBL17969767 0.60 EEF2K (0.45) EEF2KPLK1PLK2IDO1MEN1
SCHEMBL21463 0.58 MAPT (0.41) EEF2KPLK1PLK2IDO1MEN1
SCHEMBL2741115 0.58 ALDH1A1 (0.40) EEF2KPLK1PLK2IDO1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 EEF2K 2779/4885PLK1 922/4885PLK2 1465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.