SCHEMBL5588355

SCHEMBL5588355

CC1=CC(Cl)=C(C)C(=O)C1=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
USP2 O75604 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 2/20 0.33
BLM P54132 2/20 0.33
KMT2A Q03164 2/20 0.33
PLIN1 O60240 1/20 0.33
NR1I2 O75469 1/20 0.33
GSR P00390 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
CYP2D6 P10635 1/20 0.33
HSPD1 P10809 1/20 0.33
CYP2C9 P11712 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5589257 0.76 CES2 (0.40) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL5586954 0.68 MEN1 (0.33) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL5588222 0.68 MEN1 (0.33) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL9653457 0.67 MAPT (0.41) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL5589985 0.65 EEF2K (0.37) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL5589993 0.65 MAPT (0.36) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL5588953 0.64 KDM4E (0.47) MEN1ALDH1A1MAPTMAPK1KMT2A
SCHEMBL5160971 0.63 MAPT (0.40) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL12954422 0.62 MEN1 (0.32) MEN1USP2ALDH1A1GAAMAPT
SCHEMBL12852129 0.62 MEN1 (0.32) MEN1USP2ALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 MEN1 3377/4885USP2 3792/4885ALDH1A1 2181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.