SCHEMBL5590195

SCHEMBL5590195

Cc1ccccc1N=Cc1cccc(C=Nc2ccccc2C)n1.[Co]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.50
MAPT P10636 6/20 0.50
KDM4E B2RXH2 4/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
RECQL P46063 2/20 0.50
POLB P06746 1/20 0.50
MPI P34949 1/20 0.50
CYP2C9 P11712 2/20 0.46
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
PKM P14618 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
PLA2G1B P04054 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42
LMNA P02545 5/20 0.39
HPGD P15428 4/20 0.39
HTT P42858 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
HSD17B10 Q99714 1/20 0.36
NR4A1 P22736 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5589179 0.98 ALDH1A1 (0.51) ALDH1A1MAPTKDM4EL3MBTL1RECQL
SCHEMBL5589183 0.98 ALDH1A1 (0.51) ALDH1A1MAPTKDM4EL3MBTL1RECQL
Hydrochloric Acid SCHEMBL15949866 0.95 ALDH1A1 (0.49) ALDH1A1MAPTKDM4EL3MBTL1RECQL
SCHEMBL5587761 0.81 CTH (0.35) ALDH1A1MAPTKDM4ECYP2C9NPC1
SCHEMBL5693787 0.81 CTH (0.35) ALDH1A1MAPTKDM4ECYP2C9NPC1
SCHEMBL5587144 0.81 ALDH1A1 (0.54) ALDH1A1MAPTKDM4EL3MBTL1POLB
SCHEMBL6142136 0.81 ALDH1A1 (0.43) ALDH1A1MAPTKDM4EL3MBTL1RECQL
SCHEMBL16471869 0.80 NR4A1 (0.59) ALDH1A1MAPTKDM4EL3MBTL1RECQL
SCHEMBL5589937 0.79 ALDH1A1 (0.55) ALDH1A1MAPTKDM4EL3MBTL1POLB
SCHEMBL5589935 0.79 ALDH1A1 (0.55) ALDH1A1MAPTKDM4EL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US claimed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP claimed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US claimed
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 ALDH1A1 2181/4885MAPT 585/4885KDM4E 1868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.