SCHEMBL5590843

SCHEMBL5590843

CCc1ccccc1N(C(=O)O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.47
ALDH1A1 P00352 2/20 0.44
KMT2A Q03164 2/20 0.44
TSHR P16473 2/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
GLA P06280 1/20 0.44
PTPN1 P18031 3/20 0.43
TP53 P04637 1/20 0.43
LMNA P02545 2/20 0.43
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12501297 0.90 LMNA (0.46) NPSR1ALDH1A1TSHRGLAPTPN1
SCHEMBL7985518 0.87 LMNA (0.51) NPSR1ALDH1A1KMT2ATSHRNPC1
SCHEMBL9231424 0.83 ALDH1A1 (0.43) NPSR1ALDH1A1KMT2ATSHRNPC1
SCHEMBL28024187 0.80 NPSR1 (0.41) NPSR1ALDH1A1KMT2ANPC1POLB
SCHEMBL2372910 0.79 LMNA (0.56) NPSR1ALDH1A1TSHRPTPN1TP53
SCHEMBL7895277 0.78 ALDH1A1 (0.42) ALDH1A1KMT2ATSHRPOLBHTT
SCHEMBL30306601 0.78 ALDH1A1 (0.42) ALDH1A1KMT2ATSHRPOLBHTT
SCHEMBL10384054 0.77 PTPN1 (0.40) NPSR1ALDH1A1KMT2ANPC1POLB
SCHEMBL8751654 0.77 LMNA (0.43) NPSR1ALDH1A1TSHRNPC1HTT
SCHEMBL8751588 0.77 TSHR (0.52) NPSR1ALDH1A1KMT2ATSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6110265-A Ink compositions XEROX CORPORATION (US) 2000-08-29 US claimed
US-6106601-A MIXTURE CONTAINING OXAZOLINE AND THIOUREA COMPOUNDS XEROX CORPORATION (US) 2000-08-22 US claimed
EP-1857429-B1 Propulsive means for accelerating projectiles NITROCHEMIE WIMMIS AG (CH) 2013-03-27 EP disclosed
EP-1857429-A1 Propulsive means for accelerating projectiles Nitrochemie Wimmis AG (CH) 2007-11-21 EP disclosed
US-6334890-B1 COMPOSITION COMPRISED OF OXAZOLINE COMPOUND WITH SPECIFIED MELTING POINT AND ACOUSTIC LOSS VALUE, LONG CHAIN CARBAMATE, ALCOHOL COMPOUND, LIGHTFASTNESS COMPONENT, LIGHTFASTNESS ANTIOXIDANT, COLORANT XEROX CORPORATION 2002-01-01 US disclosed
US-6110265-A Ink compositions XEROX CORPORATION (US) 2000-08-29 US disclosed
US-6106601-A MIXTURE CONTAINING OXAZOLINE AND THIOUREA COMPOUNDS XEROX CORPORATION (US) 2000-08-22 US disclosed
EP-0628542-B1 Process for the preparation of organic carbamates BAYER AG (DE) 1997-04-09 EP disclosed
EP-0628542-A1 Process for the preparation of organic carbonates BAYER AG (DE) 1994-12-14 EP disclosed
EP-0373573-B1 Recording material for ink jet printing CIBA GEIGY AG (CH) 1994-06-22 EP disclosed
EP-0359710-B1 OPTICAL BRIGHTENING AGENTS CIBA-GEIGY AG (CH) 1993-06-16 EP disclosed
EP-0280650-B1 USE OF PREDETERMINED BENZTRIAZOLE DERIVATIVES AS LIGHT-PROTECTING AGENTS FOR INK JET RECORDING MATERIALS CIBA-GEIGY AG (CH) 1992-04-08 EP disclosed
EP-0373573-A1 Recording material for ink jet printing CIBA-GEIGY AG (CH) 1990-06-20 EP disclosed
EP-0359710-A1 Optical brightening agents CIBA-GEIGY AG (CH) 1990-03-21 EP disclosed
EP-0280650-A1 Use of predetermined benztriazole derivatives as light-protecting agents for ink jet recording materials CIBA-GEIGY AG (CH) 1988-08-31 EP disclosed
EP-0013958-B1 PROCESS FOR THE PREPARATION OF CARBONIC ACID ESTERS AND POLYCARBONATES BAYER AG (DE) 1982-02-10 EP disclosed