Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 18/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5590953 | 0.93 | MPL (0.67) | MPL | |
| SCHEMBL5591245 | 0.91 | MPL (0.68) | MPL | |
| SCHEMBL5591371 | 0.91 | MPL (0.63) | MPL | |
| SCHEMBL5609208 | 0.91 | MPL (0.60) | MPL | |
| SCHEMBL5591086 | 0.90 | MPL (0.58) | MPL | |
| SCHEMBL5591238 | 0.90 | MPL (0.60) | MPLABL1 | |
| SCHEMBL5591118 | 0.90 | MPL (0.74) | MPLABL1 | |
| SCHEMBL5590874 | 0.88 | MPL (0.56) | MPL | |
| SCHEMBL5591424 | 0.86 | MPL (0.52) | MPL | |
| SCHEMBL5026777 | 0.86 | MPL (0.55) | MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004038-A1 | AMINOTHIAZOLE DERIVATIVES AS AGONISTS OF THE THROMBOPOIETIN RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-01-11 | — | — | WO | disclosed |