Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 19/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591245 | 0.95 | MPL (0.68) | MPL | |
| SCHEMBL5590857 | 0.93 | MPL (0.61) | MPL | |
| SCHEMBL5591371 | 0.92 | MPL (0.63) | MPL | |
| SCHEMBL5591002 | 0.90 | MPL (0.81) | MPL | |
| SCHEMBL5591238 | 0.90 | MPL (0.60) | MPL | |
| SCHEMBL5609208 | 0.89 | MPL (0.60) | MPL | |
| SCHEMBL5591040 | 0.88 | MPL (0.62) | MPL | |
| SCHEMBL5591086 | 0.88 | MPL (0.58) | MPL | |
| SCHEMBL5591102 | 0.87 | MPL (0.58) | MPL | |
| SCHEMBL5590874 | 0.86 | MPL (0.56) | MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004038-A1 | AMINOTHIAZOLE DERIVATIVES AS AGONISTS OF THE THROMBOPOIETIN RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-01-11 | — | — | WO | claimed |
| WO-2007004038-A1 | AMINOTHIAZOLE DERIVATIVES AS AGONISTS OF THE THROMBOPOIETIN RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-01-11 | — | — | WO | disclosed |