Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745509 | 0.88 | ALDH1A1 (0.59) | ALDH1A1HTTLMNATDP1PKM | |
| SCHEMBL83885 | 0.77 | LMNA (0.61) | ALDH1A1HTTLMNATDP1PKM | |
| SCHEMBL30487906 | 0.77 | LMNA (0.61) | ALDH1A1HTTLMNATDP1PKM | |
| SCHEMBL6908458 | 0.75 | LMNA (0.59) | ALDH1A1HTTLMNATDP1PKM | |
| SCHEMBL8715253 | 0.75 | LMNA (0.59) | ALDH1A1HTTLMNATDP1PKM | |
| SCHEMBL8715228 | 0.75 | LMNA (0.59) | ALDH1A1HTTLMNATDP1PKM | |
| SCHEMBL6916815 | 0.75 | LMNA (0.59) | ALDH1A1HTTLMNATDP1PKM | |
| SCHEMBL7022903 | 0.75 | LMNA (0.59) | ALDH1A1HTTLMNATDP1PKM | |
| Water SCHEMBL11029598 | 0.75 | LMNA (0.59) | ALDH1A1HTTLMNATDP1PKM | |
| SCHEMBL6913755 | 0.75 | LMNA (0.59) | ALDH1A1HTTLMNATDP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034277-A1 | ARYL SUBSTITUTED IMIDAZO [4,5-C] PYRIDINE COMPOUNDS AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |