Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 4/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591941 | 0.76 | HTR2C (0.38) | HTR2CHTR2B | |
| SCHEMBL4931080 | 0.74 | CYP1A2 (0.40) | GAACYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10277092 | 0.73 | ANPEP (0.40) | — | |
| SCHEMBL3952833 | 0.73 | BCL2L1 (0.39) | IDO1PDPK1 | |
| SCHEMBL1634692 | 0.72 | CYP11B2 (0.41) | GAAMTNR1AMTNR1B | |
| SCHEMBL4769652 | 0.70 | PNMT (0.37) | PNMTIDO1PDPK1MTNR1AMTNR1B | |
| SCHEMBL3653495 | 0.68 | PLAU (0.41) | HTR2CHTR2BIDO1PDPK1 | |
| SCHEMBL5007618 | 0.67 | HTR2C (0.75) | GAATDP1HTR2CHTR2BRBP4 | |
| SCHEMBL5715615 | 0.67 | POLB (0.38) | GAATDP1 | |
| SCHEMBL26613553 | 0.67 | HTR2C (0.46) | GAATDP1HTR2CHTR2BRBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076104-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2007-07-05 | — | — | WO | disclosed |