Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1634692 | 0.82 | CYP11B2 (0.41) | KDM1A | |
| SCHEMBL5591709 | 0.76 | GAA (0.43) | HTR2CHTR2B | |
| SCHEMBL4769652 | 0.70 | PNMT (0.37) | — | |
| SCHEMBL4289135 | 0.70 | DRD2 (0.37) | HTR2CHTR2AHTR2B | |
| SCHEMBL4282799 | 0.70 | HSD11B1 (0.36) | KDM1A | |
| SCHEMBL7610196 | 0.69 | SLC6A2 (0.36) | — | |
| SCHEMBL1383876 | 0.68 | ANPEP (0.39) | — | |
| SCHEMBL3653495 | 0.68 | PLAU (0.41) | HTR2CHTR2B | |
| SCHEMBL4283465 | 0.67 | MEN1 (0.45) | — | |
| SCHEMBL5715615 | 0.67 | POLB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076104-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2007-07-05 | — | — | WO | disclosed |