Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.46 |
| ▸ | NPC1 | O15118 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713163 | 0.81 | RAB9A (0.50) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5757471 | 0.75 | RAB9A (0.65) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8717233 | 0.75 | RAB9A (0.56) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL827403 | 0.74 | RAB9A (0.67) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11036469 | 0.73 | RAB9A (0.51) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5323730 | 0.73 | RAB9A (0.47) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL713164 | 0.73 | RAB9A (0.66) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| Methane SCHEMBL28056221 | 0.72 | RAB9A (0.64) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL16859912 | 0.72 | RAB9A (0.64) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL28205214 | 0.72 | RAB9A (0.64) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076104-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2007-07-05 | — | — | WO | disclosed |