Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884192 | 0.83 | PPARG (0.52) | ACHEMAPTPPARGPPARDPPARA | |
| SCHEMBL16231322 | 0.82 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3ALOX15CYP3A4 | |
| SCHEMBL13304652 | 0.81 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3ALOX15CYP3A4 | |
| SCHEMBL801219 | 0.81 | HDAC4 (0.48) | SLC6A2SLC6A4SLC6A3ACHEMAPT | |
| SCHEMBL16415970 | 0.80 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3ALOX15CYP3A4 | |
| SCHEMBL2160806 | 0.79 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3ALOX15CYP3A4 | |
| SCHEMBL31135381 | 0.79 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3ALOX15CYP3A4 | |
| SCHEMBL13413339 | 0.79 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3ALOX15CYP3A4 | |
| SCHEMBL11347913 | 0.79 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3ALOX15CYP3A4 | |
| SCHEMBL383209 | 0.78 | TAS1R3 (0.42) | SLC6A2SLC6A4SLC6A3ALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121389-A2 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES AS NK-I AND SEROTONIN TRANSPORTER INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |