Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.65 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.61 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592133 | 0.84 | CHRM1 (0.52) | ADRA1AADRA1BCHRM1MCHR1ALDH1A1 | |
| SCHEMBL5592226 | 0.82 | HTR1A (0.43) | ADRA1DADRA1AADRA1BCARM1PRMT6 | |
| SCHEMBL11617045 | 0.81 | ADRA1D (0.76) | ADRA1DADRA1AADRA1BCARM1PRMT6 | |
| SCHEMBL11938908 | 0.80 | ADRA1D (0.74) | ADRA1DADRA1AADRA1BCARM1PRMT6 | |
| SCHEMBL5179385 | 0.80 | ADRA1D (0.74) | ADRA1DADRA1AADRA1BCARM1PRMT6 | |
| SCHEMBL6663300 | 0.79 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BCARM1PRMT6 | |
| SCHEMBL11618865 | 0.79 | CARM1 (0.75) | ADRA1DADRA1AADRA1BCARM1PRMT6 | |
| SCHEMBL11103818 | 0.77 | CARM1 (0.73) | ADRA1DADRA1AADRA1BCARM1PRMT6 | |
| SCHEMBL11932480 | 0.77 | ADRA1D (0.70) | ADRA1DADRA1AADRA1BCARM1PRMT6 | |
| SCHEMBL10696163 | 0.77 | ADRA1D (0.70) | ADRA1DADRA1AADRA1BCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |