Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591825 | 0.84 | KDM4E (0.50) | SMN1; SMN2KDM4ESIGMAR1ALDH1A1POLB | |
| SCHEMBL2930424 | 0.82 | SIGMAR1 (0.73) | ATMSMN1; SMN2KDM4EFAAHTSHR | |
| SCHEMBL5591946 | 0.79 | CYP19A1 (0.50) | ATMSMN1; SMN2KDM4EFAAHTSHR | |
| SCHEMBL5592054 | 0.78 | KDM4E (0.59) | ATMSMN1; SMN2KDM4EFAAHTSHR | |
| SCHEMBL2931705 | 0.77 | AKR1C3 (0.65) | KDM4EFAAHSIGMAR1LMNAALDH1A1 | |
| SCHEMBL2232306 | 0.74 | SMN1; SMN2 (0.53) | ATMSMN1; SMN2KDM4EFAAHTSHR | |
| SCHEMBL22346647 | 0.74 | HRH3 (0.56) | SMN1; SMN2KDM4EFAAHTSHRLMNA | |
| SCHEMBL2850013 | 0.73 | ALDH1A1 (0.70) | SMN1; SMN2KDM4EFAAHTSHRMAPT | |
| SCHEMBL2928876 | 0.73 | CACNA2D1 (0.55) | TSHRLMNANPSR1POLBMEN1 | |
| SCHEMBL2932454 | 0.72 | L3MBTL1 (0.54) | ATMSMN1; SMN2KDM4EFAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104696-A1 | ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-09-20 | — | — | WO | disclosed |