Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592172 | 0.87 | DRD2 (0.42) | DRD2DRD3KCNH2NCF1HTR1A | |
| SCHEMBL5592270 | 0.84 | DRD2 (0.39) | DRD2DRD3KCNH2NCF1HTR1A | |
| SCHEMBL5599366 | 0.84 | DRD2 (0.39) | DRD2DRD3KCNH2NCF1HTR1A | |
| SCHEMBL5592330 | 0.84 | DRD2 (0.39) | DRD2DRD3KCNH2NCF1HTR1A | |
| SCHEMBL5592486 | 0.78 | DRD2 (0.39) | DRD2DRD3KCNH2NCF1HTR1A | |
| SCHEMBL5611716 | 0.78 | DRD2 (0.39) | DRD2DRD3KCNH2NCF1HTR1A | |
| SCHEMBL5592512 | 0.78 | DRD2 (0.39) | DRD2DRD3KCNH2NCF1HTR1A | |
| SCHEMBL5592389 | 0.78 | DRD2 (0.39) | DRD2DRD3KCNH2NCF1HTR1A | |
| Hydrochloric Acid SCHEMBL5739570 | 0.77 | DRD2 (0.38) | DRD2DRD3KCNH2NCF1HTR1A | |
| SCHEMBL1737760 | 0.75 | ROCK2 (0.41) | DRD2DRD3NCF1HTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057742-A2 | NOVEL PIPERAZINONE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-05-24 | — | — | WO | disclosed |