Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 9/20 | 0.55 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5592282 | 0.99 | GRM5 (0.54) | GRM5TEAD3SIGMAR1CHRM2CHRM4 | |
| SCHEMBL7278874 | 0.82 | SIGMAR1 (0.67) | GRM5TEAD3SIGMAR1 | |
| SCHEMBL1946924 | 0.79 | GRM5 (0.70) | GRM5 | |
| SCHEMBL5592310 | 0.77 | GRM5 (0.42) | GRM5 | |
| Hydrochloric Acid SCHEMBL5592213 | 0.77 | GRM5 (0.41) | GRM5 | |
| SCHEMBL5592302 | 0.76 | ALDH1A1 (0.39) | SIGMAR1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13315137 | 0.76 | GRM5 (0.73) | GRM5 | |
| Hydrochloric Acid SCHEMBL5592223 | 0.75 | ALDH1A1 (0.39) | SIGMAR1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13504007 | 0.75 | GRM5 (0.72) | GRM5 | |
| SCHEMBL5592139 | 0.75 | GBA1 (0.37) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |