Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | DRD4 | P21917 | 5/20 | 0.36 |
| ▸ | DRD3 | P35462 | 5/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5592223 | 0.99 | ALDH1A1 (0.39) | ALDH1A1TP53MAPTMEN1KMT2A | |
| SCHEMBL5592132 | 0.80 | HRH2 (0.49) | ALDH1A1HRH2HRH1 | |
| Hydrochloric Acid SCHEMBL5592382 | 0.79 | HRH2 (0.48) | ALDH1A1MAPTKMT2AHPGDHTT | |
| SCHEMBL12251945 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TP53MAPTMEN1KMT2A | |
| SCHEMBL5592205 | 0.76 | GRM5 (0.55) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL14012787 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TP53MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5592282 | 0.76 | GRM5 (0.54) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL12251951 | 0.74 | ALDH1A1 (0.45) | ALDH1A1TP53MAPTKMT2APOLB | |
| SCHEMBL5592138 | 0.72 | MEN1 (0.47) | ALDH1A1TP53MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5592211 | 0.71 | MEN1 (0.46) | ALDH1A1TP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |