Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | IDH1 | O75874 | 2/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592394 | 0.87 | MEN1 (0.35) | HRH3 | |
| SCHEMBL5599159 | 0.86 | ELANE (0.35) | ELANECNR2EGLN1TNKS2CHIA | |
| SCHEMBL5592307 | 0.84 | HSD11B1 (0.36) | ELANECHIA | |
| SCHEMBL5165411 | 0.82 | ROCK2 (0.38) | ELANECNR2EGLN1CHIAHRH3 | |
| SCHEMBL5164538 | 0.81 | ELANE (0.36) | ELANECNR2EGLN1TNKS2CHIA | |
| SCHEMBL5166374 | 0.81 | ELANE (0.38) | ELANECNR2EGLN1CHIAHRH3 | |
| SCHEMBL5758903 | 0.73 | MCHR1 (0.38) | — | |
| SCHEMBL6110811 | 0.72 | ELANE (0.36) | ELANECNR2TNKS2CHIA | |
| SCHEMBL5592318 | 0.72 | MEN1 (0.36) | CNR2HRH3PARP14 | |
| SCHEMBL5210531 | 0.71 | HRH3 (0.35) | EGLN1HRH3PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057742-A2 | NOVEL PIPERAZINONE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-05-24 | — | — | WO | disclosed |