Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.42 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.42 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5592275 | 0.99 | MEN1 (0.49) | MEN1CYP1A2HTR1ACYP2C9CYP2C19 | |
| SCHEMBL5592253 | 0.96 | HTR1A (0.46) | MEN1CYP1A2HTR1ACYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL5592288 | 0.95 | HTR1A (0.45) | MEN1CYP1A2HTR1ACYP2C9CYP2C19 | |
| SCHEMBL5329926 | 0.85 | USP2 (0.48) | MEN1CYP1A2HTR1ACYP2C19HTR7 | |
| SCHEMBL5810111 | 0.82 | KDM1A (0.51) | MEN1HTR1AKMT2AADRA1ADRD2 | |
| Hydrochloric Acid SCHEMBL5805233 | 0.81 | KDM1A (0.50) | MEN1HTR1AKMT2AADRA1ADRD2 | |
| SCHEMBL5592141 | 0.80 | SLC6A1 (0.65) | MEN1CYP1A2HTR1ACYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL5592234 | 0.79 | SLC6A1 (0.64) | MEN1CYP1A2HTR1ACYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL5818499 | 0.76 | KMT2A (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5592122 | 0.76 | SLC6A1 (0.63) | MEN1CYP1A2HTR1ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |