Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.65 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.65 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.65 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5592234 | 0.99 | SLC6A1 (0.64) | SLC6A1SLC6A12SLC6A11SLC6A13HTR1A | |
| SCHEMBL5592122 | 0.95 | SLC6A1 (0.63) | SLC6A1SLC6A12SLC6A11SLC6A13HTR1A | |
| Hydrochloric Acid SCHEMBL5592131 | 0.94 | SLC6A1 (0.62) | SLC6A1SLC6A12SLC6A11SLC6A13HTR1A | |
| Hydrochloric Acid SCHEMBL11254208 | 0.85 | HTR1A (0.67) | SLC6A1SLC6A12SLC6A11SLC6A13HTR1A | |
| SCHEMBL5330447 | 0.84 | SLC6A1 (0.60) | SLC6A1SLC6A12SLC6A11SLC6A13HTR1A | |
| SCHEMBL11808412 | 0.80 | DRD2 (0.66) | SLC6A1SLC6A12SLC6A11SLC6A13HTR1A | |
| SCHEMBL5592286 | 0.80 | MEN1 (0.50) | SLC6A1SLC6A12SLC6A11SLC6A13HTR1A | |
| SCHEMBL29462287 | 0.79 | SLC6A1 (1.00) | SLC6A1SLC6A12SLC6A11SLC6A13HTR1A | |
| SCHEMBL4293184 | 0.79 | SLC6A1 (1.00) | SLC6A1SLC6A12SLC6A11SLC6A13HTR1A | |
| Hydrochloric Acid SCHEMBL5592275 | 0.79 | MEN1 (0.49) | SLC6A1SLC6A12SLC6A11SLC6A13HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |