Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5592211 | 0.99 | MEN1 (0.46) | MEN1KMT2ATP53AKR1C3HRH2 | |
| SCHEMBL5592381 | 0.79 | CHRM1 (0.44) | GAAALDH1A1 | |
| SCHEMBL9470544 | 0.78 | KEAP1 (0.48) | POLBSMN1; SMN2 | |
| SCHEMBL19588475 | 0.77 | ADRA1B (0.47) | MEN1KMT2APOLBSMN1; SMN2GAA | |
| SCHEMBL5592305 | 0.75 | MEN1 (0.36) | MEN1KMT2ATP53AKR1C3POLB | |
| SCHEMBL5592132 | 0.75 | HRH2 (0.49) | HRH2HRH1GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL5599015 | 0.74 | MEN1 (0.35) | MEN1KMT2ATP53AKR1C3POLB | |
| SCHEMBL5592315 | 0.74 | AKR1C3 (0.44) | MEN1KMT2ATP53AKR1C3POLB | |
| Hydrochloric Acid SCHEMBL5592382 | 0.74 | HRH2 (0.48) | KMT2AHRH2HRH1GAAALDH1A1 | |
| SCHEMBL5592302 | 0.72 | ALDH1A1 (0.39) | MEN1KMT2ATP53HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |