Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592325 | 0.86 | NCF1 (0.36) | NCF1KMT2AHTR7MEN1BRD9 | |
| SCHEMBL5592316 | 0.84 | DRD2 (0.37) | NCF1KMT2AMEN1BRD9BRD4 | |
| SCHEMBL1738179 | 0.81 | ROCK2 (0.39) | NCF1KMT2AHTR7MEN1BRD9 | |
| SCHEMBL1738872 | 0.81 | ROCK2 (0.39) | NCF1KMT2AHTR7MEN1BRD9 | |
| SCHEMBL1738835 | 0.81 | ROCK2 (0.39) | NCF1KMT2AHTR7MEN1BRD9 | |
| SCHEMBL5592394 | 0.80 | MEN1 (0.35) | NCF1KMT2AHTR7MEN1BRD9 | |
| SCHEMBL1737234 | 0.79 | ROCK2 (0.39) | NCF1KMT2AHTR7MEN1BRD9 | |
| SCHEMBL1737818 | 0.79 | ROCK2 (0.39) | NCF1KMT2AHTR7MEN1BRD9 | |
| SCHEMBL1738621 | 0.79 | ROCK2 (0.39) | NCF1KMT2AHTR7MEN1BRD9 | |
| SCHEMBL5592174 | 0.78 | SLC6A2 (0.35) | NCF1KMT2AMEN1BRD9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057742-A2 | NOVEL PIPERAZINONE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-05-24 | — | — | WO | disclosed |