Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.64 |
| ▸ | CTSK | P43235 | 4/20 | 0.64 |
| ▸ | CTSL | P07711 | 3/20 | 0.64 |
| ▸ | CTSB | P07858 | 2/20 | 0.64 |
| ▸ | GPR6 | P46095 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5592630 | 0.96 | CTSL (0.65) | CTSSCTSKCTSLCTSBGPR6 | |
| SCHEMBL5592572 | 0.95 | CTSS (0.70) | CTSSCTSKCTSLCTSBTBK1 | |
| Trifluoroacetic Acid SCHEMBL5592612 | 0.95 | CTSL (0.65) | CTSSCTSKCTSLCTSBGPR6 | |
| Trifluoroacetic Acid SCHEMBL5592743 | 0.93 | CTSL (0.62) | CTSSCTSKCTSLCTSBHDAC6 | |
| Trifluoroacetic Acid SCHEMBL5592935 | 0.93 | CTSL (0.55) | CTSSCTSKCTSLCTSBGPR6 | |
| Trifluoroacetic Acid SCHEMBL5592881 | 0.92 | CTSL (0.66) | CTSSCTSKCTSLCTSBGPR6 | |
| SCHEMBL5592915 | 0.92 | CTSS (0.72) | CTSSCTSKCTSLCTSBTBK1 | |
| SCHEMBL5592755 | 0.91 | CTSS (0.73) | CTSSCTSKCTSLCTSBCYP2C9 | |
| Trifluoroacetic Acid SCHEMBL5592844 | 0.91 | CTSL (0.61) | CTSSCTSKCTSLCTSBGPR6 | |
| SCHEMBL8242433 | 0.90 | CTSL (0.71) | CTSSCTSKCTSLCTSBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |