Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14605917 | 0.86 | ALDH1A1 (0.55) | ALDH1A1LMNATSHRRAB9AMEN1 | |
| SCHEMBL6250715 | 0.72 | KMT2A (0.69) | ALDH1A1LMNATSHRMEN1NPC1 | |
| SCHEMBL5954845 | 0.72 | CYP19A1 (0.60) | ALDH1A1LMNATSHRRAB9AMEN1 | |
| SCHEMBL27787149 | 0.71 | GHSR (0.44) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL5908646 | 0.70 | USP2 (0.52) | ALDH1A1LMNATSHRRAB9AMEN1 | |
| SCHEMBL4408776 | 0.69 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL3079086 | 0.68 | ALDH1A1 (0.50) | ALDH1A1LMNATSHRRAB9AMEN1 | |
| SCHEMBL10969069 | 0.68 | ALDH1A1 (0.59) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL5549102 | 0.68 | KMT2A (0.71) | ALDH1A1LMNATSHRRAB9AMEN1 | |
| SCHEMBL6014923 | 0.68 | KMT2A (0.75) | ALDH1A1LMNATSHRRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029021-A1 | 1,5-SUBSTITUTED TETRAZOLES AS THERAPEUTIC COMPOUNDS | THE UNIVERSITY OF EDINBURGH (GB) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007029021-A1 | 1,5-SUBSTITUTED TETRAZOLES AS THERAPEUTIC COMPOUNDS | THE UNIVERSITY OF EDINBURGH (GB) | 2007-03-15 | — | — | WO | disclosed |