Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10969069 | 0.88 | ALDH1A1 (0.59) | ALDH1A1TSHRHRH3LMNAMAPK1 | |
| SCHEMBL18387989 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TSHRHRH3LMNAMAPK1 | |
| SCHEMBL31272309 | 0.80 | TSHR (0.43) | ALDH1A1TSHRHRH3LMNAMAPK1 | |
| SCHEMBL12141920 | 0.80 | SLC1A3 (0.55) | ALDH1A1TSHRLMNAKDM4EMAPT | |
| SCHEMBL4518149 | 0.79 | MAPK1 (0.56) | ALDH1A1TSHRHRH3LMNAMAPK1 | |
| SCHEMBL4405905 | 0.77 | ALDH1A1 (0.57) | ALDH1A1TSHRHRH3LMNAMAPK1 | |
| SCHEMBL3035928 | 0.77 | LMNA (0.62) | ALDH1A1TSHRHRH3LMNAMAPK1 | |
| SCHEMBL12141924 | 0.75 | NPSR1 (0.53) | ALDH1A1TSHRLMNAKDM4EMAPT | |
| SCHEMBL7314086 | 0.75 | PAX8 (0.48) | ALDH1A1TSHRHRH3LMNAMAPK1 | |
| SCHEMBL7314092 | 0.75 | PAX8 (0.48) | ALDH1A1TSHRHRH3LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-7449447-B2 | Peptidomimetic NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2008-11-11 | — | — | US | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |